Extent of Resection and Survival in Glioblastoma Multiforme
نویسندگان
چکیده
منابع مشابه
Extent of Resection and Survival in Glioblastoma Multiforme.
OBJECTIVE The influence of the degree of resection on survival in patients with glioblastoma multiforme is still under discussion. The highly controlled 5-aminolevulinic acid study provided a unique platform for addressing this question as a result of the high frequency of "complete" resections, as revealed by postoperative magnetic resonance imaging scans achieved by fluorescence-guided resect...
متن کاملSurvival and functional status after resection of recurrent glioblastoma multiforme.
OBJECTIVE To determine the selection factors for and results of second resections performed to treat recurrent glioblastoma multiforme (GM), we studied 301 patients with GM who were treated from the time of diagnosis using two prospective clinical protocols. METHODS The patients were prospectively followed from the time of diagnosis, using clinical and radiographic criteria after maximal surg...
متن کاملRole of Intra-operative MRI (iMRI) in Improving Extent of Resection and Survival in Patients with Glioblastoma Multiforme.
Multiple intraoperative aids have been introduced to improve the extent of resection (EOR) in Glioblastoma Multiforme (GBM) patients, avoiding any new neurological deficits. Intraoperative MRI (iMRI) has been debated for its utility and cost for nearly two decades in neurosurgical literature. Review of literature suggests improved EOR in GBM patients who underwent iMRI assisted surgical resecti...
متن کاملExtent of Resection in Glioblastoma.
The article by Nam and de Groot provides a good overview of treatment options and considerations forglioblastoma. Surgery is a critical mainstay providing diagnostic and therapeutic benefits. The importance of extent of resection for glioblastoma has been debated for decades. Not only important at diagnosis, the relevanceof extent of resection at recurrence is increasing as patients with gliobl...
متن کاملPrognostic implications of resection extent for patients with glioblastoma multiforme: a meta-analysis.
INTRODUCTION Surgery is the primary treatment of glioblastoma multiforme (GBM), and a greater extent of resection (EOR) has been shown to be associated with improved survival. Our objective was to perform a meta-analysis comparing the 1-year overall survival (OS) and 1-year progression-free survival (PFS) of GBM patients who receive total resection, incomplete resection, or biopsy only. EVIDE...
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ژورنال
عنوان ژورنال: Neurosurgery
سال: 2009
ISSN: 0148-396X,1524-4040
DOI: 10.1227/01.neu.0000346231.57554.44